منابع مشابه
PROSTANOIDS - PROSTAGLANDINS, PROSTACYCLINS and THROMBOXANES
1. Nomenclature and Structures of Prostanoids The prostanoids are part of a family of biologically active lipids derived from the action of cyclooxygenases or prostaglandin synthases upon the twenty-carbon essential fatty acids or eicosanoids. They can be further subdivided into three main groups, the prostaglandins, prostacyclins and thromboxanes, each of which is involved in some aspect of th...
متن کاملMixed messages: modulation of inflammation and immune responses by prostaglandins and thromboxanes.
Virtually every organism has evolved mechanisms by which, upon stimulation, lipids are released from plasma membranes and metabolized into mediators capable of changing cellular physiology. As these lipids are present at the first site exposed to external challenge, they provide an ideal substrate for the synthesis of defensive mediators and homeostatic regulators. One such group of lipid media...
متن کاملA role for prostaglandins and thromboxanes in the exposure of platelet fibrinogen receptors.
Exposure of fibrinogen receptors by a variety of agonists is a prerequisite for platelet aggregation. Because the synthesis of prostaglandins and thromboxane A2 also occurs during platelet aggregation we wondered whether these agents participate in the exposure of platelet fibrinogen receptors. Therefore, we measured the binding of human 125I-fibrinogen to gel-filtered normal human platelets af...
متن کاملFast atom bombardment and collision-induced dissociation of prostaglandins and thromboxanes: Some examples of charge remote fragmentation.
The mass spectra of products found by collisional activation of selected prostaglandins and thromboxanes were studied by tandem mass spectrometry as barium carboxylate salts and as carboxylate anions. Collision-induced dissociation (CID) of these closed shell ions generated by fast atom bombardment mass spectrometry reveals a wealth of structural information for these hydroxy acids. Decompositi...
متن کاملProstaglandins
Knowledge of the structure and synthesis of antibodies (immunoglobulins) has developed to a remarkable degree in the last decade. Distinct classes of immunoglobulin (yG, yM, -yA, yD, yE, and their subgroups) have been identified and shown to consist of fixed numbers of light and heavy polypeptide chains organized in pairs. Each polypeptide has a segment of variable amino acid sequence; the spec...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 1983
ISSN: 0014-5793
DOI: 10.1016/0014-5793(83)80285-3